Spero Therapeutics Inc. (NASDAQ: SPRO) Stock Information | RedChip
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Spero Therapeutics Inc. (NASDAQ: SPRO)
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$2.92
+0.1240 ( +4.43% ) 185.3K

Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate, being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.

Clinical Trial Pipeline Stages


Drug Name Stage
Tebipenem HBr (previously SPR994): oral carbapenemDetailsBacterial infection, Urinary tract infection Phase 3
SPR206DetailsLung disease, Bacterial infection Phase 2
SPR720DetailsLung disease, Bacterial infection Phase 2a
SPR720DetailsBacterial infection, Lung disease Failed

Market Data


Open $2.92
Previous Close $2.80
Volume 185.3K
Market Cap $162.12M
Day Range $2.77 - $2.94
52 Week Range $1.80 - $3.22
Shares Outstanding 57.90M
Change % +4.43%
Net Change ▲ 0.1240
Insider Ownership 0.00%
Exchange NASDAQ
SectorHealthcare
IndustryBiotechnology: Pharmaceutical Preparations
IPO Year2017
CountryUnited States
UnderwriterIPO Intelligence Only

Insider Ownership Transactions

Total Amount Purchased: -2,306,857.00

Date Type Amount Purchased Purchaser
2023-10-10 Sale -20000.00 Tregoning Kathleen
2023-10-10 Sale -20000.00 Deshpande Milind
2023-10-10 Sale -20000.00 THOMAS FRANK E
2023-10-10 Sale -20000.00 Smith Cynthia
2023-10-10 Sale -20000.00 Pottage John C Jr
2023-09-15 Sale -39496.00 HAMED KAMAL
2023-08-30 Sale -1854.00 Keutzer Timothy
2023-08-30 Sale -1854.00 JOSEPH TAMARA L
2023-08-30 Sale -9040.00 Mahadevia Ankit
2023-08-30 Sale -1854.00 Shukla Sath

SEC Filings


Form Type Description Pages Date
8-k 8K-related 34 Nov 13, 2025
10-q Quarterly Reports 65 Nov 13, 2025
4 Insider transactions 1 Nov 12, 2025
4 Insider transactions 1 Sep 03, 2025
4 Insider transactions 1 Sep 03, 2025
8-k 8K-related 33 Aug 12, 2025
10-q Quarterly Reports 61 Aug 12, 2025
8-k 8K-related 12 Jun 18, 2025
4 Insider transactions 1 Jun 16, 2025
4 Insider transactions 1 Jun 16, 2025

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